TAMS brings you information as it becomes available on upcoming clinical trials in Australia.
Phase 2 Study of TL-895 for Indolent Systemic Mastocytosis
Status: Recruiting in Perth and Sydney
Study title: STUDY TL-895-201 by Telios Pharma, Inc.
Australian sponsor: Medpace Australia, Pty Ltd
Study site: Campbelltown Hospital
Head Investigator: Dr Hannah Hu
Purpose: TL-895 is an experimental kinase inhibitor that may decrease inflammation and improve immune function without affecting natural defense cells. Part A of this study aims to determine the safety and tolerability of TL-895 in patients with indolent systemic mastocytosis (ISM).
Participation details: In this randomised double-blind study adults 18 years or older with ISM will receive one of four oral doses of TL-895 or a placebo, along with their ongoing best supportive care. There is an 80 per cent chance of being assigned TL-895 and a 20 per cent chance of receiving a placebo.
Clinical contact: Study Nurse, Pamela Burton (Pamela.burton@health.
More information: Visit the ClinicalTrials.gov website
Blueprint Medicines Corporation’s HARBOR study
Status: Recruiting in Brisbane and Victoria
Two Australian hospitals are participating in Blueprint Medicines Corporation’s HARBOR study – The Alfred Hospital in Victoria and Princess Alexandra Hospital in Brisbane.
This study is testing BLU-263, an investigational study drug, in people with indolent systemic mastocytosis (ISM).
More information: Visit the ClinicalTrials.gov website
Cogent Apex Clinical Trial for Advanced Systemic Mastocytosis
Status: Recruiting in Kingswood NSW, Southport Qld and Melbourne Vic
Diagnosis: Advanced Systemic Mastocytosis: Aggressive, Systemic Mastocytosis with an Associated Hematologic Neoplasm, Mast Cell Leukemia
Peter MacCallum Cancer Centre
Primary Investigator: Dr. Isaac Goncalves
Clinical Coordinator: Stephanie Gervasoni
Nepean Hospital
Primary Investigator: Dr. Stephen Fuller
Clinical Coordinators: Elyssa Deakin and Rachelle Carter
Gold Coast University Hospital
Primary Investigator: Dr. Tengfong Ng
Clinical Trial Coordinators: Jefferson Aguila and Carla Henry
If you are interested in applying for the Apex Clinical Trial, please speak with your GP or specialist and ask for a referral from your GP or specialist for a referral to the relevant centre or hospital.
More information: Visit the ClinicalTrials.gov website | Visit the ANZCTR website
